A9501
Adenosine 3′,5′-cyclic monophosphate
≥98.5% (HPLC), powder, PKA activator
동의어(들):
3′,5′-Cyclic AMP, Adenosine 3′,5′-cyclophosphate, cAMP
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모든 사진(2)
About This Item
실험식(Hill 표기법):
C10H12N5O6P
CAS Number:
Molecular Weight:
329.21
Beilstein:
52645
EC Number:
MDL number:
UNSPSC 코드:
41106305
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.77
추천 제품
Product Name
Adenosine 3′,5′-cyclic monophosphate, ≥98.5% (HPLC), powder
Quality Level
분석
≥98.5% (HPLC)
양식
powder
색상
white
mp
260 °C (dec.) (lit.)
solubility
H2O: 10 mg/mL, clear, colorless (pH of aqueous solution is approx. 3.0. The sodium salt (A6885) is about 20× more soluble.)
저장 온도
−20°C
SMILES string
Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O
InChI
1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
InChI key
IVOMOUWHDPKRLL-KQYNXXCUSA-N
유전자 정보
human ... OPRK1(4986)
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애플리케이션
Adenosine 3′,5′-cyclic monophosphate has been used:
- as cell culture medium supplement in embryonic spinal neurons
- as a component of ringer solution for perfusion studies
- to induce neuroendocrine differentiation in human lung cancer cell lines
생화학적/생리학적 작용
Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). The cAMP/PKA signaling pathway inhibits cell proliferation, induces differentiation and leads to apoptosis.
Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis.
특징 및 장점
This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.