B6292

GF 109203X hydrochloride

≥95%

• 동의어(들): 3-[1-(Dimethylaminopropyl)indol-3-yl]-4-(indol-3-yl)maleimide hydrochloride, Bisindolylmaleimide I hydrochloride
• 실험식(Hill 표기법): C₂₅H₂₄N₄O₂ · HCl
• CAS Number: 176504-36-2
• Molecular Weight: 448.94
• MDL number: MFCD00236429
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24891903
• NACRES: NA.77

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 200
• 분석: ≥95%
• 양식: solid
• solubility: methanol: 10 mg/mL, clear, orange to red
• 저장 온도: 2-8°C
• SMILES string: Cl.CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c3c[nH]c4ccccc34)c5ccccc15
• InChI: 1S/C25H24N4O2.ClH/c1-28(2)12-7-13-29-15-19(17-9-4-6-11-21(17)29)23-22(24(30)27-25(23)31)18-14-26-20-10-5-3-8-16(18)20;/h3-6,8-11,14-15,26H,7,12-13H2,1-2H3,(H,27,30,31);1H
• InChI key: XRAMWNCMYJHGGH-UHFFFAOYSA-N

설명

일반 설명

GF 109203X prevents collagen-triggered adenosine and three phosphate (ATP) secretion. It also inhibits collagen and α-thrombin-induced platelet aggregation. It functions as an inhibitor of glycogen synthase kinase-3 (GSK-3). GF 109203X also functions as an anti-inflammatory agent.

애플리케이션

GF 109203X hydrochloride has been used to inhibit protein kinase C in human neuroblastoma-derived kelly cells.

생화학적/생리학적 작용

Inhibitor of protein kinase C; potent inhibitor of GSK-3.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)