B9934

BTA-1

≥98% (HPLC), solid

• 동의어(들): 2-(4´-Methylaminophenyl)benzothiazole
• 실험식(Hill 표기법): C₁₄H₁₂N₂S
• CAS Number: 439858-28-3
• Molecular Weight: 240.32
• MDL number: MFCD04974146
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24724428
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solid
• 색상: yellow
• solubility: DMSO: soluble ~10 mg/mL
• 저장 온도: 2-8°C
• SMILES string: CNc1ccc(cc1)-c2nc3ccccc3s2
• InChI: 1S/C14H12N2S/c1-15-11-8-6-10(7-9-11)14-16-12-4-2-3-5-13(12)17-14/h2-9,15H,1H3
• InChI key: FHJRKGXJBXPBGA-UHFFFAOYSA-N
• 유전자 정보: human ... APP(351)

설명

생화학적/생리학적 작용

BTA-1 is a fluorescent thioflavin-T derivative with 50-fold higher affinity for β-amyloid aggregates.

BTA-1 is a probe for β-amyloid aggregates; fluorescent thioflavin-T derivative; exhibits high affinity for amyloid deposits; displays 50-fold higher affinity than thioflavin-T; selectively stains cerebral plaques and cerebrovascular amyloid deposits in the brains of PS1/APP transgenic mice, as well as Aβ fibrils in postmortem brain tissue obtained from AD patients; crosses the blood brain barrier.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)