C125

(±)-CGP-12177A

≥98% (HPLC), solid

• 동의어(들): (±)-CGP-12177 hydrochloride, 4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-1, 3-dihydro-2H-benzimidazol-2-one hydrochloride
• 실험식(Hill 표기법): C₁₄H₂₁N₃O₃ · HCl
• CAS Number: 64208-32-8
• Molecular Weight: 315.80
• MDL number: MFCD00069230
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277768
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solid
• 색상: white
• solubility: DMSO: >10 mg/mL
• SMILES string: Cl.CC(C)(C)NCC(O)COc1cccc2NC(=O)Nc12
• InChI: 1S/C14H21N3O3.ClH/c1-14(2,3)15-7-9(18)8-20-11-6-4-5-10-12(11)17-13(19)16-10;/h4-6,9,15,18H,7-8H2,1-3H3,(H2,16,17,19);1H
• InChI key: YQVFCYCTITZLSX-UHFFFAOYSA-N
• 유전자 정보: human ... ADRB1(153), ADRB2(154), ADRB3(155)

설명

애플리케이션

(±)-CGP-12177A has been used as a β-Adrenergic receptor agonist:

• to evaluate the dissociation constant (Kd) by frontal affinity chromatography
• to study its cardiostimulant effects on rat ventricular cardiomyocytes
• to study its binding affinity in α_1D-adrenoceptors expressed in rat BHK-21 cells

생화학적/생리학적 작용

β-adrenoceptor nonconventional partial agonist.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)