C1305

Cafestol acetate

≥98%

• 실험식(Hill 표기법): C₂₂H₃₀O₄
• CAS Number: 81760-48-7
• Molecular Weight: 358.47
• MDL number: MFCD00133152
• UNSPSC 코드: 12352205
• PubChem Substance ID: 24892399
• NACRES: NA.79

속성

• Quality Level: 100
• 분석: ≥98%
• 양식: powder
• 기술: HPLC: suitable
• 색상: white to off-white
• 저장 온도: 2-8°C
• SMILES string: CC(=O)OCC1(O)CC23CCC4c5ccoc5CCC4(C)C2CCC1C3
• InChI: 1S/C22H30O4/c1-14(23)26-13-22(24)12-21-9-5-17-16-7-10-25-18(16)6-8-20(17,2)19(21)4-3-15(22)11-21/h7,10,15,17,19,24H,3-6,8-9,11-13H2,1-2H3
• InChI key: PTGGVIKFNQSFBY-UHFFFAOYSA-N

설명

애플리케이션

Cafestol acetate has been used to determine the effects of coffee on heat shock response (HSR).

생화학적/생리학적 작용

Cafestol is a coffee-specific diterpene. It has anti-carcinogenic and anti-inflammatory activities. Cafestol stimulates apoptosis in cells associated with colorectal and renal cancer (Caki cells). It is used to study mechanisms of anti-oxidation related to hydrogen peroxide induced oxidative stress and DNA damage. Cafestol increases the level of glutathione (GSH), by stimulating γ-glutamylcysteine synthetase. It acts as a chemopreventive agent by inducing cytochrome P-450.

기타 정보

Furan-containing diterpene from green coffee beans.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)