C3660
Complement C9 from human serum
≥150,000 C9H50 units/mg (using C9 deficient serum)
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보기 변경
20000 UNITS
CA$155.00
100000 UNITS
CA$477.00
About This Item
추천 제품
관련 카테고리
1 of 4
이 품목 | W270709 | M48805 | W488401 |
|---|---|---|---|
| organoleptic apple; musty; fruity | organoleptic apple; musty; fruity | organoleptic - | organoleptic coriander; green; sweet |
| grade Fragrance grade, natural, Kosher | grade FG, Fragrance grade, Halal, Kosher | grade - | grade FG, Fragrance grade, Halal, Kosher, natural |
| food allergen no known allergens | food allergen no known allergens | food allergen - | food allergen no known allergens |
| documentation see Safety & Documentation for available documents | documentation see Safety & Documentation for available documents | documentation - | documentation see Safety & Documentation for available documents |
| assay ≥98% | assay ≥98% | assay 99% | assay ≥95% |
| agency follows IFRA guidelines, meets purity specifications of JECFA | agency follows IFRA guidelines, meets purity specifications of JECFA | agency - | agency follows IFRA guidelines |
애플리케이션
Complement C9 from human serum is an essential part of the terminal complement system. It has been a topic in cancer research, where extracellular phosphorylation by ecto-PK of K562 cells on serine residues may serve as a protective mechanism against complement in tumor cells. Additionally, it can be used as a biomarker (in fucosylated form) for squamous cell lung cancer, as patients tend to show elevated levels of C9 protein.
생화학적/생리학적 작용
Complement component C9 is the final component of the membrane attack complex (MAC) responsible for cell lysis by complement. CD59 binds to both C8 and C9 and prevents assembly of an active MAC, protecting cells against lytic activity.[1]
품질
Functionally pure by a sensitive hemolytic assay using deficient sera.
물리적 형태
Supplied as a solution in phosphate buffered saline, pH 7.2.
기타 정보
View more information on the complement pathway at www.sigma-aldrich.com/enzymeexplorer
면책조항
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Storage Class Code
10 - Combustible liquids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Relationship between sensory and instrumental analysis for tomato flavor.
Baldwin EA, et al.
J. Am. Soc. Hort. Sci., 123(5), 906-915 (1998)
B D Whitaker et al.
Journal of agricultural and food chemistry, 48(6), 2040-2043 (2000-07-11)
Conjugated triene (CT) oxidation products of alpha-farnesene have long been thought to be involved in development of superficial scald in apple fruit. Early studies found that CT hydroperoxides and the volatile 6-methyl-5-hepten-2-one (MHO) are major in vitro autoxidation products of
Thangavel Rajagopal et al.
Behavioural processes, 85(1), 58-67 (2010-06-16)
In ungulates the process of chemical communication by urinary scent marking has been directly related to reproductive dominance, territorial defense and proximity to resources. The differences in the frequency of urine marking and chemical composition of urine of males Antelope
E Sprecher et al.
Antonie van Leeuwenhoek, 49(4-5), 493-499 (1983-11-01)
The accumulation of volatile metabolites in cultures of 34 strains comprising ten species of the genus Ceratocystis (Ascomycetes) has been investigated under defined culture conditions. The identified compounds include short-chain alcohols and esters, lower terpenes, terpenoids, and 2-phenylethyl acetate. Certain
W Reichardt
Canadian journal of microbiology, 27(1), 144-147 (1981-01-01)
Certain norcarotenoids, which have recently been found as excretion products of freshwater cyanobacteria and algae, are potent inhibitors of different metabolic functions in heterotrophic bacteria. 6-Methylhept-5-en-2-one showed the strongest effects and acted as a noncompetitive inhibitor of both glucose uptake
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