C6303

Calphostin C from Cladosporium cladosporioides

≥90% (HPLC), powder

• 동의어(들): UCN-1028c
• 실험식(Hill 표기법): C₄₄H₃₈O₁₄
• CAS Number: 121263-19-2
• Molecular Weight: 790.76
• MDL number: MFCD00133155
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24892857
• NACRES: NA.77

속성

• 생물학적 소스: microbial (Cladosporium cladosporioides)
• Quality Level: 200
• 분석: ≥90% (HPLC)
• 양식: powder
• 색상: red to brown
• solubility: DMF: 1 mg/mL; DMSO: 1 mg/mL; ethanol: 1 mg/mL
• 저장 온도: −20°C
• SMILES string: COc1cc(O)c2C(=O)C(OC)=C(CC(C)OC(=O)Oc3ccc(O)cc3)c4c5C(CC(C)OC(=O)c6ccccc6)=C(OC)C(=O)c7c(O)cc(OC)c(c57)c1c24
• InChI: 1S/C44H38O14/c1-20(56-43(50)22-10-8-7-9-11-22)16-25-31-32-26(17-21(2)57-44(51)58-24-14-12-23(45)13-15-24)42(55-6)40(49)34-28(47)19-30(53-4)36(38(32)34)35-29(52-3)18-27(46)33(37(31)35)39(48)41(25)54-5/h7-15,18-21,45-47H,16-17H2,1-6H3
• InChI key: SRJYZPCBWDVSGO-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Highly specific inhibitor of protein kinase C (IC₅₀ = 50 nM); requires light for activation. At higher concentrations (100 nM or greater), it has been shown to inhibit cell proliferation and induce apoptosis in vitro.

특징 및 장점

This compound is featured on the Phospholipase D and PKC pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)