C8645

Cinoxacin

• 동의어(들): 1-Ethyl-1,4-dihydro-4-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid
• 실험식(Hill 표기법): C₁₂H₁₀N₂O₅
• CAS Number: 28657-80-9
• Molecular Weight: 262.22
• EC Number: 249-133-8
• MDL number: MFCD00056776
• UNSPSC 코드: 51102829
• PubChem Substance ID: 24278343
• NACRES: NA.85

속성

• 양식: powder or crystals
• Quality Level: 200
• 항생제 활성 스펙트럼: Gram-negative bacteria
• 동작 모드: DNA synthesis | interferes; enzyme | inhibits
• SMILES string: CCN1N=C(C(O)=O)C(=O)c2cc3OCOc3cc12
• InChI: 1S/C12H10N2O5/c1-2-14-7-4-9-8(18-5-19-9)3-6(7)11(15)10(13-14)12(16)17/h3-4H,2,5H2,1H3,(H,16,17)
• InChI key: VDUWPHTZYNWKRN-UHFFFAOYSA-N

설명

일반 설명

Chemical structure: quinolone

애플리케이션

Cinoxacin was used to study the rat renal organic anion transporter 1 (OAT1). It is used to study fluoroquinolone-resistant Streptococcus pyogenes.

생화학적/생리학적 작용

Cinoxacin is a synthetic antimicrobial agent that interferes with DNA replication by inhibiting DNA gyrase and topoisomerase IV (topo IV) through tight DNA binding. The mechanism of action of cinoxacin is comparable to nalidixic acid. Cinoxacin is effective against Gram-negative bacteria and is often used to treat urinary tract infections caused by E. coli, Proteus mirabilis, Proteus vulgaris and Klebsiella sp.

기타 정보

Keep container tightly closed in a dry and well-ventilated place.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)