모든 사진(1)
About This Item
Linear Formula:
ClC6H4CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
199.63
Beilstein:
2416150
EC Number:
MDL number:
UNSPSC 코드:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.32
추천 제품
양식
powder
Quality Level
mp
263 °C (dec.) (lit.)
저장 온도
−20°C
SMILES string
N[C@@H](Cc1ccc(Cl)cc1)C(O)=O
InChI
1S/C9H10ClNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m0/s1
InChI key
NIGWMJHCCYYCSF-QMMMGPOBSA-N
유전자 정보
human ... TPH1(7166), TPH2(121278)
mouse ... TPH1(21990), TPH2(216343)
rat ... TPH1(24848), TPH2(317675)
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관련 카테고리
애플리케이션
4-Chloro-L-phenylalanine (L-PCPA) has been used:
- to block serotonin synthesis by inhibiting tryptophan hydroxylase (TPH)
- to study its behavioral and electrographic effects on epileptic senegalese baboon (Papio papio)
- as a substrate for Chromobacterium violaceum phenylalanine hydroxylase
- to incubate sea urchin embryos for immunohistochemistry
생화학적/생리학적 작용
4-Chloro-L-phenylalanine (L-PCPA) inhibits the synthesis of 5-hydroxytryptamine (5-HT). 4-Chloro-DL-phenylalanine (PCPA) depletes the serotonin levels in the brain by its inhibitory effect on tryptophan hydroxylase (Tph). Studies support the protective effects of PCPA against monocrotaline-induced pulmonary vascular remodeling as well as in lung inflammation.
Tryptophan hydroxylase inhibitor.
포장
Bottomless glass bottle. Contents are inside inserted fused cone.
관련 제품
제품 번호
설명
가격
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.