C8791

Monoclonal Anti-Cytokeratin Peptide 14 antibody produced in mouse

clone CKB1, ascites fluid

• 동의어(들): Anti-CK14, Anti-EBS1, Anti-EBS1A, Anti-EBS1B, Anti-EBS1C, Anti-EBS1D, Anti-EBS3, Anti-EBS4, Anti-K14, Anti-NFJ
• MDL number: MFCD00162249
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: ascites fluid
• 항체 생산 유형: primary antibodies
• 클론: CKB1, monoclonal
• 포함: 15 mM sodium azide
• 종 반응성: human
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; immunohistochemistry (frozen sections): suitable; indirect immunofluorescence: 1:200 using methacarn-fixed, paraffin-embedded human tissue sections
• 동형: IgM
• UniProt 수납 번호: P02533
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... KRT14(3861)

설명

일반 설명

Monoclonal Anti-Cytokeratin Peptide 14 (mouse IgM isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Keratin 14 (KRT14) is expressed in keratinocytes and localized to the basal epidermal layer. The gene is mapped to human chromosome 17q21 and encodes an intermediate filament.

특이성

The antibody reacts with myoepithelial cells in various organs (parotid, submandibular, mammary, prostate, and sweat glands) as well as with the basal layer of certain squamous epithelium (exocervical, laryngeal epithelium).

면역원

human callus keratins.

애플리케이션

Monoclonal Anti-Cytokeratin Peptide 14 antibody produced in mouse has been used in indirect immunofluorescence or immunoperoxidase techniques.

생화학적/생리학적 작용

Keratin 14 (KRT14) is associated with maintaining cellular stability. Mutation in the KRT14 gene leads to epidermolysis bullosa simplex, a genetic disorder. It is known to promote angiogenesis, cell migration and proliferation in cancer cells.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable