모든 사진(2)

주요 문서

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D1771

5′-Deoxyadenosine

Name: 5′-Deoxyadenosine
Brand: SIGMA

methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase substrate

동의어(들):

5′-dAdo

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모든 사진(2)

About This Item

실험식(Hill 표기법):

C₁₀H₁₃N₅O₃

CAS Number:

4754-39-6

Molecular Weight:

251.24

MDL number:

MFCD00056003

UNSPSC 코드:

41106305

PubChem Substance ID:

24893539

NACRES:

NA.51

추천 제품

Slide 1 of 10

1 of 10

CLS4580

Corning^® high content imaging plate

Sigma-Aldrich

A9384

S-(5′-Adenosyl)-L-homocysteine

Sigma-Aldrich

D5011

5′-Deoxy-5′-(methylthio)adenosine

Sigma-Aldrich

A9251

Adenosine

Sigma-Aldrich

A7007

S-(5′-Adenosyl)-L-methionine chloride dihydrochloride

Sigma-Aldrich

260585

5′-Deoxy-5′-methylthioadenosine

Sigma-Aldrich

A8626

Adenine

Sigma-Aldrich

H3393

Heparin sodium salt from porcine intestinal mucosa

Sigma-Aldrich

01890

Adenosine

Sigma-Aldrich

H4784

Heparin sodium salt from porcine intestinal mucosa

생물학적 소스

synthetic (organic)

Quality Level

200

분석

≥98% (TLC)

양식

powder

solubility

hot water: 19.60-20.40 mg/mL, clear, colorless

저장 온도

2-8°C

SMILES string

C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23

InChI

1S/C10H13N5O3/c1-4-6(16)7(17)10(18-4)15-3-14-5-8(11)12-2-13-9(5)15/h2-4,6-7,10,16-17H,1H3,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1

InChI key

XGYIMTFOTBMPFP-KQYNXXCUSA-N

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애플리케이션

5′-Deoxyadenosine has been used:

as a standard in mass spectroscopy
as an inhibitor for screening thymidine phosphorylase activity
as a substrate in 5′-Deoxyadenosine deaminase (DadD) assay

생화학적/생리학적 작용

5′-Deoxyadenosine is a substrate for the enzyme methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase in microbes. 5′-Deoxyadenosine is a byproduct of cleavage of S-adenosylmethionine (SAM). High levels of 5′-Deoxyadenosine inhibits SAM dependent enzymes. It also inhibits biotin synthase (BioB) and lipoyl synthase (LipA) enzymes.