D3669

3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester)

powder

• 동의어(들): DTSP, Di(N-succinimidyl) 3,3′-dithiodipropionate, Dithiobis(succinimidyl propionate), Lomant’s reagent
• 실험식(Hill 표기법): C₁₄H₁₆N₂O₈S₂
• CAS Number: 57757-57-0
• Molecular Weight: 404.42
• Beilstein: 1518074
• EC Number: 260-931-5
• MDL number: MFCD00042045
• UNSPSC 코드: 12352106
• PubChem Substance ID: 24893777
• NACRES: NC.07

속성

• 양식: powder
• Quality Level: 200
• 반응 적합성: reagent type: cross-linking reagent
• solubility: chloroform: 50 mg/mL; DMF: soluble; acetone: soluble
• 저장 온도: −20°C
• SMILES string: O=C(CCSSCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O
• InChI: 1S/C14H16N2O8S2/c17-9-1-2-10(18)15(9)23-13(21)5-7-25-26-8-6-14(22)24-16-11(19)3-4-12(16)20/h1-8H2
• InChI key: FXYPGCIGRDZWNR-UHFFFAOYSA-N

설명

일반 설명

3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) is a homobifunctional cross-linking reagent containing a cleavable disulfide linkage. It is typically coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5).

애플리케이션

3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) has been used as a protein cross-linker.

특징 및 장점

The disulfide linkage is cleavable by mild reduction.

주의사항

Avoid use of reducing agents during coupling reactions.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves