D6196

Dimebon dihydrochloride hydrate

≥98% (HPLC)

• 동의어(들): 2,8-Dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride hydrate, Dimebolin dihydrochloride hydrate, Dimeboline dihydrochloride hydrate, Dimebone dihydrochloride hydrate
• 실험식(Hill 표기법): C₂₁H₂₅N₃ · 2HCl · xH₂O
• CAS Number: 97657-92-6
• Molecular Weight: 392.37 (anhydrous basis)
• MDL number: MFCD17215933
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329798824
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to off-white
• solubility: H₂O: ≥10 mg/mL
• 저장 온도: 2-8°C
• SMILES string: O.Cl.Cl.CN1CCc2c(C1)c3cc(C)ccc3n2CCc4ccc(C)nc4
• InChI: 1S/C21H25N3.2ClH.H2O/c1-15-4-7-20-18(12-15)19-14-23(3)10-9-21(19)24(20)11-8-17-6-5-16(2)22-13-17;;;/h4-7,12-13H,8-11,14H2,1-3H3;2*1H;1H2
• InChI key: QQHQMWVYYVVAOV-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Mechanism of neuroprotection and cognition enhancement is not certain, but Dimebon blocks both cholinesterase and the NMDA receptor simultaneously and also appears to block the action of neurotoxic β-amyloid proteins and inhibit L-type calcium channels, and may exert a neuroprotective effect by blocking a novel target that involves mitochondrial pores.

특징 및 장점

This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H315,H319
• 예방조치 성명서: P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable