D7321

Diosmetin

• 동의어(들): 3′,5,7-Trihydroxy-4′-methoxyflavone, 4′-Methylluteolin, 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one, Luteolin 4′-methyl ether
• 실험식(Hill 표기법): C₁₆H₁₂O₆
• CAS Number: 520-34-3
• Molecular Weight: 300.26
• Beilstein: 294492
• EC Number: 208-291-8
• MDL number: MFCD00017425
• UNSPSC 코드: 12352205
• PubChem Substance ID: 329798848
• NACRES: NA.25

속성

• 분석: ≥98% (HPLC)
• Quality Level: 200
• 양식: powder
• 색상: light yellow to yellow
• solubility: DMSO: 1 mg/mL, clear, faintly yellow to greenish-yellow
• 응용 분야: metabolomics; vitamins, nutraceuticals, and natural products
• 저장 온도: 2-8°C
• SMILES string: COc1ccc(cc1O)C2=CC(=O)c3c(O)cc(O)cc3O2
• InChI: 1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3
• InChI key: MBNGWHIJMBWFHU-UHFFFAOYSA-N

설명

일반 설명

Diosmetin is a methylated aglycone flavone of diosmin. It is present abundantly in citrus fruits, Olea europaea L. (olive tree) leaves, and in the legume of Acacia farnesiana tree.

애플리케이션

Diosmetin has been used to test its protective effects on chronic stress memory and cognitive impairment in mice model.

생화학적/생리학적 작용

Diosmetin exhibits anti-inflammatory, anti-cancer, antimicrobial, phytoestrogenic, and neuroprotective properties. It displays cytoprotective effects against lipopolysaccharide (LPS)-induced acute lung injury (ALI) by inhibiting nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP3) inflammasome and activating nuclear factor erythroid 2–related factor 2 (Nrf2).

Flavonoid from Citrus limon. Antioxidant. Inhibits carcinogen activation by inhibiting the CYP1A1 enzyme.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable