D7802

Daidzein

≥98% (TLC), powder, carbonic anhydrase (CA) inhibitor

• 동의어(들): 4′,7-Dihydroxy­iso­flavone, 7-Hydroxy-3-(4-hydroxy­phenyl)-4H-1-benzo­pyran-4-one, 7-Hydroxy-3-(4-hydroxy­phenyl)­chromone, Isoaurostatin
• 실험식(Hill 표기법): C₁₅H₁₀O₄
• CAS Number: 486-66-8
• Molecular Weight: 254.24
• Beilstein: 231523
• EC Number: 207-635-4
• MDL number: MFCD00016954
• UNSPSC 코드: 12352202
• PubChem Substance ID: 24278030
• NACRES: NA.77

속성

• Product Name: Daidzein, ≥98%, synthetic
• 생물학적 소스: synthetic
• Quality Level: 200
• 분석: ≥98%
• 양식: powder
• mp: >290 °C
• solubility: DMSO: 10 mg/mL
• 저장 온도: −20°C
• SMILES string: Oc1ccc(cc1)C2=COc3cc(O)ccc3C2=O
• InChI: 1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H
• InChI key: ZQSIJRDFPHDXIC-UHFFFAOYSA-N
• 유전자 정보: human ... ESR1(2099), ESR2(2100), UGT1A4(54657) ; mouse ... Aldh1a2(19378), Hexa(15211), Maoa(17161) ; rat ... Aldh1a2(116676)

설명

일반 설명

Daidzein is an isoflavone present in soy. It regulates oxidative stress, angiogenesis, cell growth and apoptosis. Daidzein has antioxidant, antiestrogenic and antiatherogenic properties. It provides protection against osteoporosis.

애플리케이션

Daidzein has been used:

• as a control to evaluate fertility in rats
• to study its effects on ovarian cancer
• to simulate in vitro antioxidant activity

생화학적/생리학적 작용

Daidzein is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. Arrests cell cycle at G₁ in Swiss 3T3 cells.

Soy isoflavone daidzein protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.

포장

Packaged under Argon.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319
• 예방조치 성명서: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves