E1407

Monoclonal Anti-Erythropoietin antibody produced in rat

clone 148438, purified immunoglobulin, lyophilized powder

• 동의어(들): Anti-EP, Anti-EPO, Anti-Epo
• MDL number: MFCD02096326
• UNSPSC 코드: 51111800
• NACRES: NA.41

속성

• 생물학적 소스: rat
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 148438, monoclonal
• 양식: lyophilized powder
• 종 반응성: mouse
• 기술: neutralization: suitable
• 동형: IgG2a
• UniProt 수납 번호: P07321
• 저장 온도: −20°C
• 유전자 정보: mouse ... Epo(13856)

설명

일반 설명

Erythropoietin (Epo) is a pleotropic cytokine that promotes erythropoiesis or proliferation and differentiation of red blood cell precursors. Epo is mainly produced by liver cells in fetal stages, by kidneys under hypoxic conditions; liver and brain also secrete Epo is less amounts. The red blood cell production is stimulated when Epo binds and activates the Epo receptor (EpoR) dimer. EpoR directly regulates the signalling by Jak2, PI3K, NF-κB, STAT5A and STAT5B. Epo also inhibits apoptosis of erythroid progenitors by downregulating Fas and FasL. The expression of Epo is under the control of the transcription factor hypoxia inducible factor (HIF). Erythropoietin exhibits disease-modifying effects in infectious diseases and chronic inflammatory disorders
Monoclonal Anti-Erythropoietin antibody specifically reacts with mouse Erythropoietin.

면역원

purified, CHO cell-derived recombinant mouse erythropoietin.

애플리케이션

Monoclonal Anti-Erythropoietin antibody is suitable for neutralization reactions.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)