E5156

Epinastine hydrochloride

≥98% (HPLC), solid

• 동의어(들): 9,13b-Dihydro-1H-dibenz[cf]imidazo[1,5-a]azepine hydrochloride, WAL-801Cl
• 실험식(Hill 표기법): C₁₆H₁₅N₃ · HCl
• CAS Number: 108929-04-0
• Molecular Weight: 285.77
• MDL number: MFCD00933434
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24894608
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solid
• 저장 조건: desiccated
• 색상: white
• solubility: H₂O: 38 mg/mL
• 주관자: Boehringer Ingelheim
• 저장 온도: 2-8°C
• SMILES string: Cl[H].NC1=NCC2N1c3ccccc3Cc4ccccc24
• InChI: 1S/C16H15N3.ClH/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16;/h1-8,15H,9-10H2,(H2,17,18);1H
• InChI key: VKXSGUIOOQPGAF-UHFFFAOYSA-N
• 유전자 정보: human ... HRH1(3269)

설명

일반 설명

Epinastine has antihistamine functions. In mast cells, it may modulate cytokine and chemokine production. In dendritic cells, it controls T helper cell mediated immune response. Epinastine hydrochloride does not traverse the brain barrier. Oral dosage of epinastine hydrochloride is prescribed for children with sleep-disordered breathing (SDB) and nasal inflammation. Ophthalmic solution of epinastine is effective for allergic conjunctivitis.

생화학적/생리학적 작용

Epinastine hydrochloride is a non-sedating H1 histamine receptor antagonist.

특징 및 장점

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301
• 예방조치 성명서: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges