E6758

Ethylenediaminetetraacetic acid

anhydrous, crystalline, BioReagent, suitable for cell culture

• 동의어(들): (Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid
• Linear Formula: (HO₂CCH₂)₂NCH₂CH₂N(CH₂CO₂H)₂
• CAS Number: 60-00-4
• Molecular Weight: 292.24
• Beilstein: 1716295
• EC Number: 200-449-4
• MDL number: MFCD00003541
• UNSPSC 코드: 12161700
• eCl@ss: 39030907
• PubChem Substance ID: 24894634
• NACRES: NA.25

속성

• Grade: anhydrous
• Quality Level: 200
• 제품 라인: BioReagent
• 분석: ≥98.5%
• 양식: crystalline
• 반응 적합성: reagent type: chelator
• 기술: cell culture | mammalian: suitable
• pH: 2.5 (23 °C, 10 g/L)
• mp: 250 °C (dec.) (lit.)
• solubility: 3 M NaOH: 100 mg/mL
• density: 1.46 g/cm³ at 20 °C
• 양이온 미량물: C: 40.7-41.5%; N: 9.3-9.8%
• SMILES string: OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O
• InChI: 1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)
• InChI key: KCXVZYZYPLLWCC-UHFFFAOYSA-N

설명

애플리케이션

Ethylenediaminetetraacetic acid has been used:

• as a component of peptide dilution buffer for intracellular BH3 (Bcl-2 homology (BH) domain) profiling and validation
• as a medium component in the hepatic stellate cell (HSCs) culture
• as a component of homogenization buffer for protein extraction from eye tissues
• for stopping benzonase reaction in lysis buffer

생화학적/생리학적 작용

Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood samples. EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia. EDTA along with tetracycline imparts serves as root conditioning agent and provides relief in gum infection. EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis. Calcium Disodium EDTA administration is effective in slowing down the progression of chronic kidney disease.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H319
• 예방조치 성명서: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves