F1678

R-(−)-Fluoxetine hydrochloride

>98% (HPLC), solid

• 동의어(들): (R)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine hydrochloride
• 실험식(Hill 표기법): C₁₇H₁₈NOF₃ · HCl
• CAS Number: 114247-09-5
• Molecular Weight: 345.79
• MDL number: MFCD04040065
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278433
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: >98% (HPLC)
• 양식: solid
• 저장 조건: desiccated
• 색상: white
• solubility: H₂O: soluble >10 mg/mL
• 주관자: Eli Lilly
• SMILES string: Cl[H].CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2
• InChI: 1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m1./s1
• InChI key: GIYXAJPCNFJEHY-PKLMIRHRSA-N
• 유전자 정보: human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

설명

애플리케이션

R-(−)-Fluoxetine hydrochloride has been used as a serotonin reuptake inhibitor:

• to study its effects on the embryoid body (EB) morphogenesis
• in combination with muscimol hydrobromide (MUS) as well as individually to study its neurotoxic effects on neuronal cells grown on multielectrode array (MEA) chips
• to study its effects as an endocrine disruption inducer in Pimephales promelas

생화학적/생리학적 작용

Fluoxetine exhibits anti-depressant activity by increasing the serotonin levels in the neuron synaptic space. It also exhibits therapeutic effects against depression and other mood disorders.

Selective serotonin reuptake inhibitor.

특징 및 장점

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H302,H315,H318
• 예방조치 성명서: P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves