F2177

Follistatin 288 from mouse

>95% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder

• 동의어(들): FS-288
• MDL number: MFCD03456879
• UNSPSC 코드: 51111800
• NACRES: NA.32

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 재조합: expressed in baculovirus infected Sf21 cells
• 분석: >95% (SDS-PAGE)
• 양식: lyophilized powder
• 효능: 0.04-0.4 mg per mL
• 분자량: calculated mol wt ~31 kDa
• 포장: pkg of 25 μg
• 저장 조건: avoid repeated freeze/thaw cycles
• 불순물: endotoxin, tested
• UniProt 수납 번호: P47931
• 저장 온도: −20°C
• 유전자 정보: mouse ... Fst(14313)

설명

일반 설명

FST (follistatin) is an activin-binding protein, and exists in two isoforms due to alternate splicing, FS288 and FS315. It is a glycoprotein with a single chain, and acts as an activin antagonist. It has a high level of expression in fetal membranes and placenta.

생화학적/생리학적 작용

FST (follistatin) binds to and regulates activins, which in turn are TGF (transforming growth factor)-β superfamily members. The expression level of FST and its binding partner activin A is elevated in inflammatory disorders. The activin A-follistatin system plays an essential role in the modulation of glucose and lipid metabolism, which might have an overall effect on fetal growth. In adipose tissue, it facilitates the adipogenic differentiation of progenitor cells.

High affinity activin-binding protein that can act as an activin antagonist.

물리적 형태

Recombinant Mouse Follistatin 288 is supplied as a approximately 25 μg of protein lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% TFA containing 1.25 mg of bovine serum albumin.

분석 메모

The biological activity is measured by its ability to neutralize activin-induced erythroid differentiation on K562 cells.

안전성 정보

• 픽토그램: GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H315,H318
• 예방조치 성명서: P280 - P305 + P351 + P338 + P310
• Hazard Classifications: Eye Dam. 1 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable