F9786

Fibroblast Growth Factor-Basic Heparin Stabilized human

recombinant, expressed in E. coli, aqueous solution, suitable for cell culture

• 동의어(들): rhbFGF
• CAS Number: 106096-93-9
• MDL number: MFCD00081382
• UNSPSC 코드: 12352202
• NACRES: NA.77

속성

• Product Name: Fibroblast Growth Factor-Basic Heparin Stabilized human, FGF-Basic, recombinant, expressed in E. coli, sterile-filtered, aqueous solution, suitable for cell culture
• 생물학적 소스: human
• 재조합: expressed in E. coli
• 무균: sterile-filtered
• 양식: aqueous solution
• 효능: 0.03-3.0 ng/mL ED₅₀/EC₅₀
• 품질: endotoxin tested
• 포장: pkg of 1 and 5 mL
• 기술: cell culture | mammalian: suitable
• UniProt 수납 번호: P09038
• 저장 온도: 2-8°C
• 유전자 정보: human ... FGF2(2247)

설명

일반 설명

Fibroblast growth factor 2 (FGF2), a canonical member, belongs to the fibroblast growth factor family.

애플리케이션

Fibroblast Growth Factor-Basic Heparin Stabilized human has been used to culture Brown Norway rat yolk sac epithelial cells transformed with mouse sarcoma virus (BN/MSV). It has also been used in the preparation of serum-free mouse tubal epithelium growth medium (M-TE-GM) to culture primary tubal epithelium (TE) cells.

생화학적/생리학적 작용

Fibroblast growth factor 2 (FGF2) participates in tissue development and repair. It is also involved in embryonic development, angiogenesis, bone regeneration, stem cell self-renewal, and wound healing. The basic fibroblast growth factor (bFGF) plays a key role in the progression and maintenance of the nervous system. FGF2 binds to the FGF receptor (FGFR) and activates the extracellular signal-regulated kinase (ERK) pathway, which controls cellular behavior, using heparan sulfates (HS)/heparin as a cofactor. bFGF stimulates cell proliferation, differentiation, and migration in a variety of cell types. In cultured astrocytes from rat brain, recombinant human basic fibroblast growth factor (rhbFGF) may induce nerve growth factor (NGF) secretion. It is the heparin stabilized form of a natural mitogenic growth factor used in cell culture applications to study cell signaling and to promote fibroblast and endothelial cell growth and survival.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)