G1921

Glypican 3 human

recombinant, expressed in NSO cells

• UNSPSC 코드: 12352202
• NACRES: NA.26

속성

• 생물학적 소스: human
• Quality Level: 200
• 재조합: expressed in NSO cells
• 분석: ≥97% (SDS-PAGE)
• 양식: lyophilized powder
• UniProt 수납 번호: P51654
• 저장 온도: −20°C
• 유전자 정보: human ... GPC3(2719)

설명

일반 설명

Glypican-3, a cell surface protein, is highly expressed in hepatocellular carcinoma (HCC) and few other human cancers including melanoma. It is a heparan sulfate proteoglycan and is present on the cell surface. Under non-reducing conditions in SDS-PAGE, the glycanated glypican 3 appears as a smear with an apparent molecular mass of 60 - 100 kDa†

생화학적/생리학적 작용

Sulfate proteoglycan attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor. Regulates cell survival and inhibits cell proliferation during normal development. Potential use as marker for early disease detection.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in PBS containing 50 μg of bovine serum albumin per 1 μg of cytokine.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable