G4256

Galactose-1-phosphate Uridyltransferase from galactose-adapted yeast

Type IV, lyophilized powder, 20-60 units/mg protein (modified Warburg-Christian)

• 동의어(들): GALT, UDP glucose:α-D-galactose-1-phosphate uridyltransferase
• CAS Number: 9016-11-9
• EC 번호: 2.7.7.12 (BRENDA, IUBMB)
• MDL number: MFCD00131120
• UNSPSC 코드: 12352204
• NACRES: NA.54

속성

• 유형: Type IV
• Quality Level: 300
• 양식: lyophilized powder
• 특이 활성도: 20-60 units/mg protein (modified Warburg-Christian)
• 구성: Protein, 15-35%
• 외래 활성: 6-phosphogluconate dehydrogenase ≤0.5%; UDP glucose pyrophosphorylase and galactokinase ≤0.2%
• 저장 온도: −20°C

설명

일반 설명

Research area: Cell Signaling

Galactose-1-phosphate uridyltransferase (GALT) is a galactose metabolizing enzyme that facilitates the simultaneous conversion of uridine diphosphoglucose (UDP-glucose) and galactose-1-phosphate (gal-1P) to uridine diphosphogalactose (UDP-galactose) and glucose-1-phosphate. Classic Galactosemia (CG) is an inherited metabolic condition caused by deficiency of GALT activity. GALT gene is mapped to human chromosome 9p13. Deficiency of GALT results in type 1 galactosemia.

애플리케이션

Galactose-1-phosphate Uridyltransferase from galactose-adapted yeast has been used to perform enzyme assays.

단위 정의

One unit will form 1.0 μmole of glucose 1-phosphate from UDP-glucose, galactose 1-phosphate and NADP⁺ per min at pH 8.7 at 25 °C as detected by a coupled system using phosphoglucomutase.

물리적 형태

Contains buffer salts as citrate and reduced glutathione

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)