G5419

Anti-GAD1/GAD2 Antibody

mouse monoclonal, K-87

• 동의어(들): Anti-GAD 67
• MDL number: MFCD06202147
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• Product Name: Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody produced in mouse, clone K-87, purified antibody
• 생물학적 소스: mouse
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: purified antibody
• 항체 생산 유형: primary antibodies
• 클론: K-87, monoclonal
• 분자량: antigen 67 kDa
• 종 반응성: rat, mouse, human
• 농도: ~1 mg/mL
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500-1:20,000 (with antigen-retrieval step); western blot: 1:500-1:20,000 using mouse brain extract
• 동형: IgG1κ
• UniProt 수납 번호: Q99259
• 배송 상태: dry ice
• 저장 온도: −70°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... GAD1(2571) ; mouse ... Gad1(14415) ; rat ... Gad1(24379)

설명

일반 설명

Glutamic Acid Decarboxylase 67 (GAD67) is encoded by the gene glutamic acid decarboxylase 1 (GAD1). GAD1 gene is located on the human chromosome at 2q31.1. GAD67 is localized in the dendrites and cell bodies.

특이성

Reacts specifically with GAD67. Does not crossreact with GAD65.

면역원

This peptide does not share homology with GAD65.

synthetic peptide from mouse GAD67 (amino acids 87-106).

애플리케이션

Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody is suitable for use in immunoblot, western blot (at 1:500-1:20,000 dilutions using mouse brain extract) and immunohistochemistry (at 1:500-1:20,000 dilutions in mouse brain sections).

Monoclonal anti-glutamic acid decarboxylase 67 (GAD67) antibody produced in mouse has been used in:

• immunohistofluorescence
• western blotting
• immunohistochemistry.

생화학적/생리학적 작용

Glutamic Acid Decarboxylase 67 (GAD67) is involved in the production of γ-amino butyric acid (GABA), a inhibitory neurotransmitter in the central nervous system (CNS). Deficiency of GAD67 leads to psychosis, schizophrenia and bipolar diseases.

물리적 형태

Solution in phosphate buffered saline containing 0.01% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)