H1007
L-Homoarginine hydrochloride
≥98% (TLC)
동의어(들):
(S)-2-Amino-6-guanidinohexanoic acid hydrochloride
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모든 사진(1)
About This Item
Linear Formula:
H2NC(=NH)NH(CH2)4CH(NH2)CO2H · HCl
CAS Number:
Molecular Weight:
224.69
Beilstein:
4016621
EC Number:
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.26
추천 제품
Product Name
L-Homoarginine hydrochloride, unnatural arginine analog
Quality Level
분석
≥98% (TLC)
양식
powder
색상
white to off-white
mp
213-215 °C (lit.)
solubility
H2O: soluble
응용 분야
peptide synthesis
SMILES string
Cl[H].N[C@@H](CCCCNC(N)=N)C(O)=O
InChI
1S/C7H16N4O2.ClH/c8-5(6(12)13)3-1-2-4-11-7(9)10;/h5H,1-4,8H2,(H,12,13)(H4,9,10,11);1H/t5-;/m0./s1
InChI key
YMKBVNVCKUYUDM-JEDNCBNOSA-N
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애플리케이션
L-Homoarginine may be used to create non-natural proteins for studies of post-translational protein modifications. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements. L-Homoarginine is used to study the mechanisms of nitric oxide production by cells via nitric oxide synthase(s). L-Homoarginine is used as a selective mammalian alkaline phosphatase isoenzyme inhibitor. The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin.
The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements.
생화학적/생리학적 작용
Homoarginine is an inhibitor of tissue nonspecific alkaline phosphatase (TNALP). It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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