H6012

4-Hydroxyestrone

≥90% (HPLC)

• 동의어(들): 1,3,5(10)-Estratriene-3,4-diol-17-one
• 실험식(Hill 표기법): C₁₈H₂₂O₃
• CAS Number: 3131-23-5
• Molecular Weight: 286.37
• MDL number: MFCD00079358
• UNSPSC 코드: 51111800
• PubChem Substance ID: 24895725
• NACRES: NA.77

속성

• 무균: non-sterile
• Quality Level: 100
• 분석: ≥90% (HPLC)
• 양식: powder
• solubility: methanol: 10 mg/mL, clear, colorless to faintly brownish-yellow
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: [H][C@]12CC[C@]3(C)C(=O)CC[C@@]3([H])[C@]1([H])CCc4c(O)c(O)ccc24
• InChI: 1S/C18H22O3/c1-18-9-8-11-10-4-6-15(19)17(21)13(10)3-2-12(11)14(18)5-7-16(18)20/h4,6,11-12,14,19,21H,2-3,5,7-9H2,1H3/t11-,12-,14+,18+/m1/s1
• InChI key: XQZVQQZZOVBNLU-QDTBLXIISA-N

설명

생화학적/생리학적 작용

4-Hydroxyestrone is an endogenous estrogen metabolite, which exhibits a strong neuroprotective effect against oxidative damage. It also provides effective protection against kanic acid-induced hippocampal oxidative damage in rats when compared to 17β-estradiol. 4-Hydroxyestrone regulates the angiogenic process during corpus luteum formation. It might be involved in an increased risk of cancer. 4-Hydroxyestrone is found in the early and mid-luteal phases.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): 199.9 °F - closed cup
• Flash Point (°C): 93.3 °C - closed cup
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)