I8026

Anti-Interleukin-8 antibody produced in goat

affinity isolated antibody, lyophilized powder

• 동의어(들): Anti-CXCL8, Anti-IL-8
• MDL number: MFCD00212220
• UNSPSC 코드: 51111800
• NACRES: NA.41

속성

• 생물학적 소스: goat
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: lyophilized powder
• 종 반응성: human
• 기술: immunocytochemistry: 5-15 μg/mL; immunohistochemistry: 5-15 μg/mL; neutralization: suitable; western blot: 0.1 μg/mL
• 저장 온도: −20°C
• 유전자 정보: human ... IL8(3576)

설명

일반 설명

Interleukin 8 (IL-8) is an 8kD, 72 amino acid residue containing cytokine that belongs to C-X-C chemokine family . The IL-8 gene is mapped to human chromosome 4q13.3.

특이성

The antibody will neutralize the biological activity of recombinant and natural human IL-8, but not recombinant human GROα.

면역원

recombinant human IL-8 (CXCL8).

애플리케이션

Anti-Interleukin-8 antibody can be used for the following :

• For neutralizing the biological activity of recombinant human IL-8 and natural human IL-8.
• Immunoblotting.
• ELISA.

Anti-Interleukin-8 antibody can be used in immunocytochemistry and immunohistochemistry.

생화학적/생리학적 작용

Interleukin 8 (IL-8) stimulates neutrophils to produce lysosomal enzymes along with myeloperoxidase, α-mannosidase and β-glucuronidase . Goat anti-Interleukin-8 antibody reacts specifically with recombinant and natural human IL-8 but not with recombinant human GROα. Elevated expression of the gene is observed in a number of cancers including chronic spontaneous urticaria and breast cancer, thus serves as a prognostic marker for the same. IL-8 regulates the metastasis and angiogenesis processes during cancer development. IL-8 is responsible for epithelial–mesenchymal transition which plays an important role in providing cancer cells the mobility to invade other neighbouring cells, thereby contributing to metastasis.

물리적 형태

Lyophilized from 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable