I9409

Monoclonal Anti-Insulin-like Growth Factor-I antibody produced in hamster

clone 126002, purified immunoglobulin, lyophilized powder

• 동의어(들): Anti-IGF-I
• MDL number: MFCD00162566
• UNSPSC 코드: 51111800
• NACRES: NA.41

속성

• 생물학적 소스: hamster
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 126002, monoclonal
• 양식: lyophilized powder
• 종 반응성: mouse
• 기술: capture ELISA: 2-8 μg/mL; neutralization: suitable; western blot: 1-2 μg/mL
• 동형: IgG1
• UniProt 수납 번호: P05017
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: mouse ... Igf1(16000)

설명

일반 설명

Insulin-like Growth Factor-I (also known as somatomedinC and somatomedin A) and insulin-like growth factor-II(IGF-II) belong to the family of insulin-like growthfactors, which are structurally homologous to proinsulin.Mature IGF-I and IGF-II are h

면역원

purified, E. coli-derived recombinant mouse insulin-like growth factor-I.

생화학적/생리학적 작용

Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver. IGF-1 acts via specific receptor, IGF-1R, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, Raf/Ras and PI3K cascades. The effects of IGF-1R signaling are important at many developmental levels from cells to organ to organism, growth, differentiation, anti-apoptosis, proliferation and transformation.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)