I9783

Monoclonal Anti-Importin α3 antibody produced in rat

clone 3D10, purified immunoglobulin, buffered aqueous solution

• 동의어(들): Anti-Imp α
• MDL number: MFCD06798707
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rat
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 3D10, monoclonal
• 양식: buffered aqueous solution
• 분자량: antigen ~60 kDa
• 종 반응성: mouse, hamster, bovine, canine, rat, human, monkey
• 기술: microarray: suitable; western blot: 2-4 μg/mL using HeLa cell extract
• 동형: IgG2a
• UniProt 수납 번호: O00629
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... KPNA4(3840) ; mouse ... Kpna4(16649) ; rat ... Kpna4(361959)

설명

면역원

recombinant mouse importin α3/Qip1.

생화학적/생리학적 작용

The gene KPNA4 (karyopherin subunit α 4) encodes a 16kDa protein, also referred to as importin α 3 belonging to the family of karyopherins (designated KPNA1 to KPNA4), that participates in the recognition of NLS (nuclear localization signal) sites and dock NLS-containing proteins destined for transport into the nuclear pore complex. It binds to translocon and participates in the sorting of INM (inner nuclear membrane)-directed integral membrane proteins. It associates with nucleoporins and functions in cargo-translocation across the nuclear membrane.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable