K4144

KB-R7943

≥98% (HPLC), powder

• 동의어(들): 2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl ester, methanesulfonate (1:1), Carbamimidothioic acid
• 실험식(Hill 표기법): C₁₆H₁₇N₃O₃S·CH₃SO₃H
• CAS Number: 182004-64-4
• Molecular Weight: 427.50
• MDL number: MFCD00952138
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329817144
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: off-white to tan
• solubility: DMSO: >10 mg/mL
• 저장 온도: 2-8°C
• SMILES string: CS(O)(=O)=O.NC(=N)SCCc1ccc(OCc2ccc(cc2)[N+]([O-])=O)cc1
• InChI: 1S/C16H17N3O3S.CH4O3S/c17-16(18)23-10-9-12-3-7-15(8-4-12)22-11-13-1-5-14(6-2-13)19(20)21;1-5(2,3)4/h1-8H,9-11H2,(H3,17,18);1H3,(H,2,3,4)
• InChI key: WGIKEBHIKKWJLG-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

KB-R7943 inhibits the reversed Na(+)/Ca(2+) exchanger, NCX.

KB-R7943 inhibits the reversed Na(+)/Ca(2+) exchanger, NCX. In cardiomyocytes, Ca2+ is released from intracellular stores during contraction, and sequestered again during relaxation. NCX is the primary mechanism that prevents Ca2+ overload due to influx of calcium across the plasma membrane.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable