L0517

Leukotriene B₄

~100 μg/mL in ethanol, ≥97%

• 동의어(들): [5S,12R]-Dihydroxy-[6Z,8E,10E,14Z]-eicosatetraenoic acid
• 실험식(Hill 표기법): C₂₀H₃₂O₄
• CAS Number: 71160-24-2
• Molecular Weight: 336.47
• EC Number: 200-578-6
• MDL number: MFCD00135630
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24896256
• NACRES: NA.77

속성

• Quality Level: 200
• 분석: ≥97%
• 양식: liquid
• 농도: ~100 μg/mL in ethanol
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: CCCCC\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC(O)=O
• InChI: 1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7+,9-6-,14-10+,15-11-/t18-,19-/m1/s1
• InChI key: VNYSSYRCGWBHLG-AMOLWHMGSA-N
• 유전자 정보: human ... LTB4R(1241) ; rat ... Ltb4r(59264)

설명

생화학적/생리학적 작용

Proinflammatory agent. Stimulates c-Fos and c-Jun proto-oncogene transcription in human monocytes. Stimulates chemotaxis, aggregation, and degranulation of polymorphonuclear leukocytes.

특징 및 장점

This compound is featured on the Leukotriene Receptors and Nuclear Receptors (PPARs) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

포장

Data sheet which accompanies each product includes special handling instructions. Except where noted, method for hydrolysis of methyl esters is also described.

안전성 정보

• 픽토그램: GHS02,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H225,H319
• 예방조치 성명서: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 1
• Flash Point (°F): 57.2 °F - closed cup
• Flash Point (°C): 14.0 °C - closed cup