L5420

Lumefantrine

• 동의어(들): (9Z)-2,7-Dichloro-9-[(4-chlorophenyl)methylene]-α-[(dibutylamino)methyl]-9H-fluorene-4-methanol, Benflumetol, CPG-56695
• 실험식(Hill 표기법): C₃₀H₃₂Cl₃NO
• CAS Number: 82186-77-4
• Molecular Weight: 528.94
• MDL number: MFCD05662268
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329817625
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• Quality Level: 100
• 양식: powder
• 색상: yellow
• solubility: DMSO: 2 mg/mL, clear (warmed)
• 주관자: Novartis
• 저장 온도: room temp
• SMILES string: CCCCN(CCCC)CC(O)c1cc(Cl)cc2C(=C/c3ccc(Cl)cc3)\c4cc(Cl)ccc4-c12
• InChI: 1S/C30H32Cl3NO/c1-3-5-13-34(14-6-4-2)19-29(35)28-18-23(33)17-27-25(15-20-7-9-21(31)10-8-20)26-16-22(32)11-12-24(26)30(27)28/h7-12,15-18,29,35H,3-6,13-14,19H2,1-2H3/b25-15-
• InChI key: DYLGFOYVTXJFJP-MYYYXRDXSA-N

설명

일반 설명

Lumefantrine, also known as benflumetol is an aryl-amino alcohol. It is a member of the group of arylamine alcohols like quinine, mefloquine and halofantrine.

애플리케이션

Lumefantrine has been used:
to study its effect on ex-vivo Plasmodium falciparum sensitivity using the tritiated hypoxanthine-based assay
as a standard in the quantification of combined tablet formulation using HPTLC
as a drug molecule in in vitro growth inhibition assay for in vitro B. caballi growth inhibition studies

생화학적/생리학적 작용

Lumefantrine is is an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria.

특징 및 장점

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable