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일반 설명
Lipodisq® reagents are novel polymers derived from styrene and maleic acid. Lipodisq® polymers are capable of forming nanosized lipid-based discoidal particles capable of incorporating membrane proteins. Lipodisqs typically have a diameter of 9-10 nm at pH 7.4.
애플리케이션
Lipodisq® reagents are novel polymers derived from styrene and maleic acid. Lipodisq polymers are capable of forming nanosized lipid-based discoidal particles capable of incorporating membrane proteins. The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents. In general, Lipodisq polymers are potentially useful in mitigating the use of detergents for the solubilization of membrane proteins. Lipodisqs typically have a diameter of 9-10 nm at pH 7.4.
The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents.
Functional pH range: 6.0 - 9.0
Functional pH range: 6.0 - 9.0
생화학적/생리학적 작용
Lipodisq® polymers are potentially useful in mitigating the use of detergents for solubilization of membrane proteins. Dissolving this product in an aqueous solution, with sufficient base (e.g. KOH, NaOH), causes hydrolysis of each anhydride moiety into two carboxylic acid/carboxylate groups. This action renders the SMA polymer soluble in aqueous media. Lipodisq® acts as a potential membrane mimic system.
법적 정보
Lipodisq is a registered trademark of Malvern Cosmeceutics Limited
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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