M0267

(±)-Methadone hydrochloride

powder, ≥98%

• 동의어(들): 6-Dimethylamino-4,4-diphenylheptan-3-one hydrochloride
• 실험식(Hill 표기법): C₂₁H₂₇NO · HCl
• CAS Number: 1095-90-5
• Molecular Weight: 345.91
• EC Number: 214-140-7
• MDL number: MFCD00058014
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24896546
• NACRES: NA.77

속성

• Quality Level: 200
• 분석: ≥98%
• 양식: powder
• 약물 제어: USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 색상: white to off-white
• solubility: H₂O: 50 mg/mL, clear, colorless to yellow
• 주관자: Novartis
• SMILES string: Cl.CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c2ccccc2
• InChI: 1S/C21H27NO.ClH/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6-15,17H,5,16H2,1-4H3;1H
• InChI key: FJQXCDYVZAHXNS-UHFFFAOYSA-N
• 유전자 정보: human ... OPRM1(4988)

설명

생화학적/생리학적 작용

μ opioid receptor agonist that desensitizes both the μ opioid receptor and the δ opioid receptor on chronic exposure; narcotic analgesic, characterized by a gradual onset of action and prolonged, milder withdrawal; may also block L-type calcium channels independently of its effects on opioid receptors.

특징 및 장점

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H300,H336
• 예방조치 성명서: P261 - P264 - P271 - P301 + P310 - P304 + P340 + P312 - P403 + P233
• Hazard Classifications: Acute Tox. 2 Oral - STOT SE 3
• 표적 기관: Central nervous system
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges