N1016

Nimesulide

• 동의어(들): N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide
• 실험식(Hill 표기법): C₁₃H₁₂N₂O₅S
• CAS Number: 51803-78-2
• Molecular Weight: 308.31
• EC Number: 257-431-4
• MDL number: MFCD00079470
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278583
• NACRES: NA.77

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 100
• 분석: ≥98% (TLC)
• 양식: powder
• solubility: ethanol: 50 mg/mL
• 저장 온도: 2-8°C
• SMILES string: CS(NC1=C(OC2=CC=CC=C2)C=C([N+]([O-])=O)C=C1)(=O)=O
• InChI: 1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3
• InChI key: HYWYRSMBCFDLJT-UHFFFAOYSA-N
• 유전자 정보: human ... ALB(213), PTGS1(5742), PTGS2(5743)

설명

일반 설명

Nimesulide, a nonsteroidal anti-inflammatory drug (NSAID) belongs to the sulfonanilide class.

애플리케이션

Nimesulide has been used as a component in the reaction mixture to determine the activity of cyclooxygenase (COX) in spleen of chickens.

생화학적/생리학적 작용

Highly selective cyclooxygenase-2 inhibitor.

Nimesulide can be used as a substitute to other nonsteroidal anti-inflammatory drugs (NSAIDs) to treat pain and inflammation of osteoarthritis for a short period. It can perform anti-inflammatory, analgesic and antipyretic activities.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301
• 예방조치 성명서: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves