N151

Nisoxetine hydrochloride

solid, ≥98% (HPLC)

• 동의어(들): (±)-γ-(2-Methoxyphenoxy)-N-methyl-benzenepropanamine hydrochloride, LY-94,939
• 실험식(Hill 표기법): C₁₇H₂₁NO₂ · HCl
• CAS Number: 57754-86-6
• Molecular Weight: 307.82
• MDL number: MFCD00153850
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277788
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solid
• 저장 조건: desiccated
• 색상: white to beige
• solubility: H₂O: 20 mg/mL; ethanol: 50 mg/mL
• SMILES string: Cl[H].CNCCC(Oc1ccccc1OC)c2ccccc2
• InChI: 1S/C17H21NO2.ClH/c1-18-13-12-15(14-8-4-3-5-9-14)20-17-11-7-6-10-16(17)19-2;/h3-11,15,18H,12-13H2,1-2H3;1H
• InChI key: LCEURBZEQJZUPV-UHFFFAOYSA-N

설명

애플리케이션

Nisoxetine has been used as a norepinephrine transport (NET) blocker in autoradiography studies. It has also been used as a NET blocker to study its effects on perivascular adipose tissue.

생화학적/생리학적 작용

Nisoxetine is a selective and potent noradrenaline reuptake inhibitor. It has a high affinity towards the noradrenaline transporter. Nisoxetine possesses antidepressant activity.

특징 및 장점

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)