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N5131

Nicotinamide guanine dinucleotide sodium salt

Name: Nicotinamide guanine dinucleotide sodium salt
Brand: SIGMA

phospodiesterase and ADP-ribosyl cyclase substrate

동의어(들):

3-(Aminocarbonyl)-1-[(2R,3R,4S,5R)-5-({[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(2-Amino-6-Oxo-1,6-Dihydro-9h-Purin-9-Yl)-3,4-Dihydroxytetrahydrofuran-2-Yl]methoxy}(Hydroxy)phosphoryl]oxy} (Hydroxy)phosphoryl]ox, NGD

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About This Item

실험식(Hill 표기법):

C₂₁H₂₈N₇O₁₅P₂

CAS Number:

5624-35-1

Molecular Weight:

680.43

MDL number:

MFCD00079505

UNSPSC 코드:

41106305

PubChem Substance ID:

24897721

NACRES:

NA.51

추천 제품

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Sigma-Aldrich

N2630

Nicotinamide 1,N⁶-ethenoadenine dinucleotide

Sigma-Aldrich

C7344

Cyclic adenosine diphosphate-ribose

Sigma-Aldrich

N5755

β-Nicotinamide adenine dinucleotide phosphate hydrate

Sigma-Aldrich

A0752

Adenosine 5′-diphosphoribose sodium salt

Sigma-Aldrich

N5655

Nicotinic acid adenine dinucleotide phosphate sodium salt

Sigma-Aldrich

N0632

β-Nicotinamide adenine dinucleotide sodium salt

Sigma-Aldrich

E3019

Esterase from porcine liver

Sigma-Aldrich

M6751

5-Methylcytosine hydrochloride

Sigma-Aldrich

P3243

Phosphodiesterase I from Crotalus adamanteus venom

Sigma-Aldrich

N4505

β-Nicotinamide adenine dinucleotide, reduced dipotassium salt

생물학적 소스

yeast

Quality Level

200

분석

≥-96%

양식

powder

solubility

H₂O: soluble-50 mg/mL, clear, almost colorless to slightly yellow

저장 온도

−20°C

SMILES string

NC(=O)C1=CC=C[N](=C1)C2OC(COP(O)(=O)OP(O)(=O)OCC3OC(C(O)C3O)n4cnc5C(=O)N=C(N)Nc45)C(O)C2O

InChI

1S/C21H28N7O15P2/c22-16(33)8-2-1-3-27(4-8)19-14(31)12(29)9(41-19)5-39-44(35,36)43-45(37,38)40-6-10-13(30)15(32)20(42-10)28-7-24-11-17(28)25-21(23)26-18(11)34/h1-4,7,9-10,12-15,19-20,29-32H,5-6H2,(H2,22,33)(H,35,36)(H,37,38)(H3,23,25,26,34)

InChI key

WWXCUPZEUROLRY-UHFFFAOYSA-N

애플리케이션

Nicotinamide guanine dinucleotide (NGD+) may be used as a preferred substrate of specific snake Trimeresurus stejnegeri venom phospodiesterase and a substrate to study the specificity and kinetics of ADP-ribosyl cyclase(s).

Nicotinamide guanine dinucleotide sodium salt has been used as a substrate for measuring the cyclase activity of the enzyme cluster of differentiation 38 (CD38). It has also been used as a substrate to fluorometrically determine the activity of CD38/ADP-ribose (ADPR).

생화학적/생리학적 작용

Nicotinamide guanine dinucleotide sodium salt is used to determine the activity of proteins that generate cyclic-ADP-ribose (cADPR) in the ADP-ribosyl cyclase family.