N7510

Nicardipine hydrochloride

powder, ≥98%

• 동의어(들): 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 2-[methyl(phenylmethyl)amino]ethyl ester hydrochloride, YC-93
• 실험식(Hill 표기법): C₂₆H₂₉N₃O₆ · HCl
• CAS Number: 54527-84-3
• Molecular Weight: 515.99
• EC Number: 259-198-4
• MDL number: MFCD00057327
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277856
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98%
• 양식: powder
• 색상: yellow
• solubility: DMSO: ~1 mg/mL; 0.1 M NaOH: insoluble; H₂O: slightly soluble; methanol: soluble
• 주관자: EKR Therapeutics
• 저장 온도: 2-8°C
• SMILES string: Cl[H].COC(=O)C1=C(C)NC(C)=C(C1c2cccc(c2)[N+]([O-])=O)C(=O)OCCN(C)Cc3ccccc3
• InChI: 1S/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16H2,1-4H3;1H
• InChI key: AIKVCUNQWYTVTO-UHFFFAOYSA-N
• 유전자 정보: human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779)

설명

생화학적/생리학적 작용

Blocks L-type voltage-dependent calcium channels; antihypertensive.

특징 및 장점

This compound was developed by EKR Therapeutics. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301 + H311 + H331
• 예방조치 성명서: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges