O100

Oxotremorine M

solid

• 동의어(들): N,N,N,-Trimethyl-4-(2-oxo-1-pyrrolidinyl)-2-butyn-1-ammonium iodide, Oxotremorine methiodide
• 실험식(Hill 표기법): C₁₁H₁₉IN₂O
• CAS Number: 63939-65-1
• Molecular Weight: 322.19
• MDL number: MFCD00055133
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277861
• NACRES: NA.77

속성

• 양식: solid
• 색상: white
• solubility: H₂O: 24 mg/mL; ethanol: 4.6 mg/mL
• 저장 온도: 2-8°C
• SMILES string: [I-].C[N+](C)(C)CC#CCN1CCCC1=O
• InChI: 1S/C11H19N2O.HI/c1-13(2,3)10-5-4-8-12-9-6-7-11(12)14;/h6-10H2,1-3H3;1H/q+1;/p-1
• InChI key: VVLMSCJCXMBGDI-UHFFFAOYSA-M
• 유전자 정보: human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

설명

애플리케이션

Oxotremorine M has been used as a muscarinic acetylcholine receptor (mAchR) agonist:

• to study its acute effects on the movement of Caenorhabditis elegans
• to treat hippocampal neurons for studying fibroblast growth factor receptor 1 (FGFR1) phosphorylation
• to induce bladder overactivity in rats

생화학적/생리학적 작용

Oxotremorine M is a nonselective muscarinic acetylcholine receptor agonist.

특징 및 장점

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) and Acetylcholine Receptors (Nicotinic) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H300 + H310 + H330
• 예방조치 성명서: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)