O2260

Mouse Osteopontin

recombinant, expressed in NSO cells, powder, suitable for cell culture

• 동의어(들): Bone Sialoprotein-1, Early T Lymphocyte Activation Protein-1 (ETA-1), OPN, Secreted Phosphoprotein 1 (Spp1)
• MDL number: MFCD03100698
• UNSPSC 코드: 12352202
• NACRES: NA.32

속성

• Product Name: Osteopontin from mouse, >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture
• 생물학적 소스: mouse
• Quality Level: 100
• 재조합: expressed in NSO cells
• 무균: sterile
• 분석: >95% (SDS-PAGE)
• 양식: lyophilized powder
• 분자량: 30 kDa by SDS-PAGE (reducing); 65 kDa by SDS-PAGE (reducing) (doublet)
• 포장: pkg of 50 μg
• 기술: cell culture | mammalian: suitable
• 불순물: endotoxin, tested
• UniProt 수납 번호: P10923
• 배송 상태: dry ice
• 저장 온도: −20°C
• 유전자 정보: mouse ... Spp1(20750)

설명

애플리케이션

Osteopontin from mouse has been used:

• to study its role in a mouse model of preterm brain injury
• as a positive control to analyze the relationship between the vascular calcification process and osteopontin (OPN) overexpression in the neointima of atherosclerotic plaques
• to study its interaction on the crystal growth process of hydroxyapatite in agarose hydrogels

생화학적/생리학적 작용

Osteopontin (OPN) is a secreted, highly acidic, calcium binding, phosphorylated glycoprotein that is chemotactic for macrophages, smooth muscle cells, endothelial cells and glial cells. In activated macrophages, OPN inhibits nitric oxide production and cytotoxicity. Human, mouse, rat, pig and bovine OPN share 40% amino acid sequence identity.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 2.5 mg bovine serum albumin.

분석 메모

The biological activity is measured by its ability to mediate 293 cell adhesion.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable