O9265

Osthole

• 동의어(들): 7-Methoxy-8-(3-methyl-2-butenyl)coumarin, 7-Methoxy-8-isopentenylcoumarin, Osthol
• 실험식(Hill 표기법): C₁₅H₁₆O₃
• CAS Number: 484-12-8
• Molecular Weight: 244.29
• MDL number: MFCD00076049
• UNSPSC 코드: 12352205
• PubChem Substance ID: 329818938
• NACRES: NA.25

속성

• 분석: ≥95% (HPLC)
• Quality Level: 200
• 양식: powder
• 색상: white
• solubility: methanol: soluble 10 mg/mL, clear, colorless
• 응용 분야: metabolomics; vitamins, nutraceuticals, and natural products
• 저장 온도: room temp
• SMILES string: COc1ccc2C=CC(=O)Oc2c1C\C=C(\C)C
• InChI: 1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3
• InChI key: MBRLOUHOWLUMFF-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Active constituent of Cnidium monnieri, a traditional Chinese medicine used for its anti-inflammatory, analgesic, and anti-lipedemic activities. Dramatically decreased lipid accumulation in a quail model. Its neuroprotective effect on MPP(+)-induced cytotoxicity in PC12 cells supports the use of osthole as a therapeutic agent for the treatment of neurodegenerative disorders. Suppression of fatty acid synthase expression in HER2-overexpressing breast cancer cells indicates osthole as a promising agent for chemotherapy.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable