O9387

Oxatomide

≥99%

• 동의어(들): 1-[3-[4-(Diphenylmethyl)-1-piperazinyl]propyl]-1,3-dihydro-2H-benzimidazol-2-one
• 실험식(Hill 표기법): C₂₇H₃₀N₄O
• CAS Number: 60607-34-3
• Molecular Weight: 426.55
• EC Number: 262-320-9
• MDL number: MFCD00211147
• UNSPSC 코드: 51111800
• PubChem Substance ID: 24278615
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥99%
• 양식: powder
• 색상: white
• solubility: DMSO: soluble; ethanol: soluble
• 주관자: Johnson & Johnson
• SMILES string: O=C1Nc2ccccc2N1CCCN3CCN(CC3)C(c4ccccc4)c5ccccc5
• InChI: 1S/C27H30N4O/c32-27-28-24-14-7-8-15-25(24)31(27)17-9-16-29-18-20-30(21-19-29)26(22-10-3-1-4-11-22)23-12-5-2-6-13-23/h1-8,10-15,26H,9,16-21H2,(H,28,32)
• InChI key: BAINIUMDFURPJM-UHFFFAOYSA-N
• 유전자 정보: human ... DRD3(1814)

설명

일반 설명

Oxatomide, a histamine H1-receptor antagonist, is bound at high levels to plasma proteins in human blood.

생화학적/생리학적 작용

Oxatomide is an anti-allergy compound. It suppresses platelet activating factor (PAF)-induced bronchoconstriction and inhibits leukotriene production.

Oxatomide, found in several antihistamines, can suppress mast cell degranulation. It can be used as an alternative to individuals with allergic rhinitis who do not or poorly respond to more established antihistamines. Oxatomide exhibits both antihistamine and anti-inflammatory properties. It exhibits therapeutic effects against asthma and vulvar lichen sclerosus.

특징 및 장점

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves