P0064

PalGly

≥98% (HPLC), solid

• 동의어(들): N-(1-Oxohexadecyl)glycine, N-Hexadecanoylglycine, Hexadecanoylaminoacetic acid, N-palmitoyl glycine
• 실험식(Hill 표기법): C₁₈H₃₅NO₃
• CAS Number: 2441-41-0
• Molecular Weight: 313.48
• MDL number: MFCD00153471
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329820003
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: solid
• 색상: white to off-white
• solubility: DMSO: >10 mg/mL
• 저장 온도: 2-8°C
• SMILES string: O=C(CCCCCCCCCCCCCCC)NCC(O)=O
• InChI: 1S/C18H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(20)19-16-18(21)22/h2-16H2,1H3,(H,19,20)(H,21,22)
• InChI key: KVTFEOAKFFQCCX-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production.

PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production. PalGly inhibits heat-evoked firing of wide dynamic range (WDR) neurons, activates calcium influx in DRG cells and stimulates NO production. Preliminary studies suggest its signaling mechanism involves GPCR-mediated cation channel activation and a Gαi/o-coupled signaling pathway, which is being further investigated.

특징 및 장점

This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)