P1851

PIPES

BioPerformance Certified, suitable for cell culture

• 동의어(들): 1,4-Piperazinediethanesulfonic acid, Piperazine-1,4-bis(2-ethanesulfonic acid), Piperazine-N,N′-bis(2-ethanesulfonic acid)
• 실험식(Hill 표기법): C₈H₁₈N₂O₆S₂
• CAS Number: 5625-37-6
• Molecular Weight: 302.37
• Beilstein: 817713
• EC Number: 227-057-6
• MDL number: MFCD00006159
• UNSPSC 코드: 12161700
• PubChem Substance ID: 24898249
• NACRES: NA.25

속성

• Grade: BioPerformance Certified; Molecular Biology
• Quality Level: 400
• 양식: crystalline powder
• 기술: cell culture | mammalian: suitable
• 불순물: endotoxin and Total Aerobic Microbial Count, tested
• 유용한 pH 범위: 6.1-7.5
• pKa(25 °C): 6.8
• mp: >300 °C (lit.)
• solubility: 1 M NaOH: 20 + 80 mL g, clear, colorless; soluble
• 응용 분야: diagnostic assay manufacturing
• 외래 활성: DNAse, Exonuclease; NICKase, Endonuclease; RNAse; Protease, none detected
• SMILES string: OS(=O)(=O)CCN1CCN(CC1)CCS(O)(=O)=O
• InChI: 1S/C8H18N2O6S2/c11-17(12,13)7-5-9-1-2-10(4-3-9)6-8-18(14,15)16/h1-8H2,(H,11,12,13)(H,14,15,16)
• InChI key: IHPYMWDTONKSCO-UHFFFAOYSA-N

설명

애플리케이션

• Sensitive Detection of Immunoglobulin G Stability Using in Real-Time Isothermal Differential Scanning Fluorimetry: Determinants of Protein Stability for Antibody-Based Therapeutics.: The use of PIPES buffer in this study was integral to maintaining the stability of immunoglobulin G during differential scanning fluorimetry. This method is crucial for evaluating the stability of antibody-based therapeutics (Moggridge et al., 2017).

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)