P4798

L-Phenylalanine Dehydrogenase from Sporosarcina sp.

lyophilized powder, ≥6 units/mg solid

• CAS Number: 69403-12-9
• EC 번호: 1.4.1.20 (BRENDA, IUBMB)
• MDL number: MFCD00151723
• UNSPSC 코드: 12352204
• NACRES: NA.54

속성

• 생물학적 소스: bacterial (Sporosarcina sp.)
• Quality Level: 200
• 양식: lyophilized powder
• 특이 활성도: ≥6 units/mg solid
• 저장 조건: dry at room temperature
• 농도: ≤100%
• 색상: white to light brown
• 응용 분야: life science and biopharma
• 저장 온도: −20°C

설명

일반 설명

Research area: CELL SIGNALING

Phenylalanine dehydrogenase is a member of a large family of amino-acid dehydrogenases, which includes glutamate dehydrogenase, alanine dehydrogenase, leucine dehydrogenase, lysine ε-dehydrogenase, and meso-a,ε-diaminopimelate D-dehydrogenase. The three known gene sequences are octomers. It has a two-domain, three-dimensional structure.

생화학적/생리학적 작용

Phenylalanine dehydrogenase (PheDH) is considered an effective enzyme to estimate the quantity of phenylalanine to distinguish phenylketonuria (PKU) disease.Moreover, it is utilized for the production of optically pure l-phenylalanine, a key component of the artificial sweetener aspartame. L-Phenylalanine dehydrogenase is a NAD+-dependent oxidoreductase that catalyzes the reversible, oxidative deamination of L-phenylalanine, which results in its degradation. L-Phenylalanine dehydrogenase is used to study phenylalanine metabolism and phenylalanine, tyrosine, and tryptophan biosynthesis.

단위 정의

One unit will oxidize 1.0 μmole of L-phenylalanine per min at pH 10.5 at 30 °C in the presence of β-NAD.

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H334
• 예방조치 성명서: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)