P5976

Anti-Platelet-Derived Growth Factor-BB antibody produced in goat

affinity isolated antibody, lyophilized powder

• 동의어(들): Anti-PDGF-BB
• MDL number: MFCD00165456
• UNSPSC 코드: 51111800
• NACRES: NA.41

속성

• 생물학적 소스: goat
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: lyophilized powder
• 종 반응성: human
• 기술: neutralization: suitable; western blot: suitable
• UniProt 수납 번호: P01127
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PDGFB(5155)

설명

일반 설명

Platelet-Derived Growth Factor-BB (PDGF-BB) is a cystine-linked homodimer that belongs to PDGF growth factor family and is expressed mainly by vascular endothelium, megakaryocytes and Leydig cells. It has key roles in regulating neurogenesis, producing proinflammatory cytokines by orbital fibroblasts in Graves′ Ophthalmopathy, cell proliferation, development, angiogenesis and cell survival. Anti-Platelet-Derived Growth Factor-BB antibody can be used for neutralizing the biological activity of recombinant human PDGF-BB, recombinant human-AB, natural human PDGF, rat PDGF-BB, and porcine PDGF-BB. It can also neutralize recombinant human PDGF-AA at 50-100 fold high IgG concentration. Goat Anti-Platelet-Derived Growth Factor-BB antibody reacts specifically with human PDGF-BB. The product has also shown less than 10% cross-reactivity for recombinant human PDGF-AA.

면역원

Recombinant human PDGF-BB expressed in Escherichia coli.

애플리케이션

Anti-Platelet-Derived Growth Factor-BB antibody can be used in immunoblotting and ELISA.

물리적 형태

Lyophilized from 0.2 μm filtered solution in phosphate buffered saline pH 7.4 with 5% trehalose.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)