P6402

Perphenazine

• 동의어(들): 4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol
• 실험식(Hill 표기법): C₂₁H₂₆ClN₃OS
• CAS Number: 58-39-9
• Molecular Weight: 403.97
• EC Number: 200-381-5
• MDL number: MFCD00056798
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278642
• NACRES: NA.77

속성

• 양식: powder
• Quality Level: 200
• 주관자: Schering Plough
• 저장 온도: 2-8°C
• SMILES string: ClC(C=C1)=CC2=C1SC3=CC=CC=C3N2CCCN4CCN(CCO)CC4
• InChI: 1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2
• InChI key: RGCVKNLCSQQDEP-UHFFFAOYSA-N
• 유전자 정보: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152), DRD2(1813), OPRS1(10280)

설명

일반 설명

Perphenazine is an antipsychotic drug used in treating schizophrenia. It modulates antioxidant levels and helps in the management of oxidative injury in schizophrenia. However, it is less effective than the clozapine drug group in improving response to oxidative injury.

생화학적/생리학적 작용

D₂ dopamine receptor antagonist; α-adrenergic receptor antagonist and σ-receptor agonist; phenothiazine antipsychotic. Inhibits glutamate dehydrogenase in vitro.

특징 및 장점

This compound was developed by Schering Plough. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H317
• 예방조치 성명서: P261 - P264 - P272 - P280 - P301 + P312 - P302 + P352
• Hazard Classifications: Acute Tox. 4 Oral - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3