P7412

Pirenzepine dihydrochloride

≥98% (TLC), powder

• 동의어(들): 5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride
• 실험식(Hill 표기법): C₁₉H₂₁N₅O₂ · 2HCl
• CAS Number: 29868-97-1
• Molecular Weight: 424.32
• EC Number: 249-907-5
• MDL number: MFCD00055214
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277863
• NACRES: NA.77

속성

• Quality Level: 200
• 분석: ≥98% (TLC)
• 양식: powder
• 색상: white to light yellow
• solubility: H₂O: 50 mg/mL
• SMILES string: Cl[H].Cl[H].CN1CCN(CC1)CC(=O)N2c3ccccc3C(=O)Nc4cccnc24
• InChI: 1S/C19H21N5O2.2ClH/c1-22-9-11-23(12-10-22)13-17(25)24-16-7-3-2-5-14(16)19(26)21-15-6-4-8-20-18(15)24;;/h2-8H,9-13H2,1H3,(H,21,26);2*1H
• InChI key: FFNMBRCFFADNAO-UHFFFAOYSA-N
• 유전자 정보: human ... CHRM1(1128)

설명

일반 설명

Pirenzepine dihydrochloride is an anticholinergic agent. It is also considered as an antiulcer drug. It is used to treat myopia, gastric and duodenal ulcers. Pirenzepine dihydrochloride induces the dimerization of muscarinic M1 receptors.

애플리케이션

Pirenzepine dihydrochloride has been used

• in transactivation of fibroblast growth factor receptor (FGFR).
• as a supplement in cell culture.
• for the stimulation of human fibroblasts

생화학적/생리학적 작용

Selective M₁ muscarinic acetylcholine receptor antagonist.

특징 및 장점

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

주의사항

Hygroscopic; store desiccated at room temperature.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)