P8013

Pargyline hydrochloride

• 동의어(들): N-Methyl-N-(2-propynyl)benzylamine hydrochloride, N-Methyl-N-propargylbenzylamine hydrochloride
• Linear Formula: C₆H₅CH₂N(CH₃)CH₂C≡CH·HCl
• CAS Number: 306-07-0
• Molecular Weight: 195.69
• Beilstein: 3699487
• EC Number: 206-175-1
• MDL number: MFCD00012492
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278153
• NACRES: NA.77

속성

• 생물학적 소스: synthetic
• Quality Level: 200
• 분석: 98% (TLC)
• 양식: powder or crystals
• mp: 160-163 °C (lit.)
• solubility: water: 50 mg/mL, clear, colorless to faintly yellow
• 저장 온도: −20°C
• SMILES string: Cl[H].CN(CC#C)Cc1ccccc1
• InChI: 1S/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H
• InChI key: BCXCABRDBBWWGY-UHFFFAOYSA-N
• 유전자 정보: human ... MAOA(4128), MAOB(4129)

설명

애플리케이션

Pargyline hydrochloride has been used:

• as a histone demethylase inhibitor to treat monocytes to investigate whether various inhibitors affect training
• to maximize uptake into dopaminergic neurons (DA) neurons in experimental rats,
• to study its effect on discolouration of medullary tissues of sclerotia of S. sclerotiorum

생화학적/생리학적 작용

Pargyline hydrochloride acts as a histone demethylase inhibitor. It has antihypertensive action.

Selective MAO-B inhibitor.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301
• 예방조치 성명서: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves