PRS3941

Anti-IRF7 (ab1) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 동의어(들): Anti-Interferon regulatory factor 7
• MDL number: MFCD02096777
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 종 반응성: human, rat, mouse
• 기술: immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProt 수납 번호: Q92985
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... IRF7(3665)

설명

일반 설명

Interferon regulatory factor 7 (IRF7) protein, a multifunctional transcription factor, is a lymphoid-specific factor expressed in the cytoplasm in B cells, plasmacytoid dendritic cells (pDCs), and monocytes in the spleen, thymus, and peripheral blood lymphocytes. IRF7 gene is located on human chromosome 11p15.5.

면역원

a peptide corresponding to 14 amino acids near the carboxy-terminus of human IRF7 .

애플리케이션

Anti-IRF7 (ab1) antibody produced in rabbit has been used in immunoblotting.

생화학적/생리학적 작용

Interferon regulatory factor 7 (IRF7) protein plays a key role in regulating the type I interferon (IFN) alpha/beta (IFNα/β) responses, which are necessary to innate and adaptive immunity. Hence IRF7 is considered as the ‘master′ controller of IFN type I production. It plays a key role in priming. IRF7 can also form homodimers or heterodimers with interferon regulatory factor 5 (IRF5) to modulate target genes. It might regulate oncogenesis and apoptosis. IRF7 plays an important role in the pathogenesis of type I diabetes. It is connected to the latency of the Epstein–Barr virus (EBV).

결합

The action of this antibody can be blocked using blocking peptide SBP3941.

물리적 형태

Solution in phosphate buffered saline containing 0.02% sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable